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Why

Circulogene?

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Circulogene is

Best-in-Class

Each patient’s cancer is unique, and understanding the origins and severity of the cancer aids oncologists to personalize the patient’s treatment plan at the time of diagnosis and throughout their cancer journey.

Circulogene’s comprehensive tumor DNA and RNA sequencing is the only plasma testing available that combines the most advanced next-generation sequencing (NGS) and polymerase chain reaction (PCR) technology to detect and monitor cfDNA and cfRNA within well-characterized, well-documented, actionable cancer-associated genes.

  • Combines NGS and PCR

  • Increased DNA & RNA yields

  • Provides the ONLY liquid PD-L1

  • Includes TMB and MSI

  • Delivers personalized, actionable reports

Key Advantages
of Circulogene

1

Better Catch Rate

By combining PCR testing for cfRNA detection and cfDNA NGS, Circulogene captures more actionable mutations and fusions. 

2

Complete Results

486 genes, DNA, RNA, PD-L1, MSI, TMB

3

Speed

Approximately 10 day turn around time.

4

Plasma PD-L1 

Circulogene’s comprehensive gene panel is the only noninvasive technique that utilizes blood to test plasma PD-L1 RNA. A 3-year landmark study demonstrated parallel survival benefits when using plasma cfRNA PD-L1 compared to tissue PD-L1 as an indication for immunotherapy. 

5

Early Stage Testing

Circulogene’s comprehensive testing platform allows for testing ALL STAGES of cancer. All patients, regardless of stage, deserve a full molecular profile to guide treatment and therapy options. 

6

Upstream Testing

Performing Circulogene NGS/PD-L1 molecular testing at the time of a biopsy ensures all newly diagnosed patients get full molecular testing, expedites the correct treatment, and reduces the risk of the wrong treatment. 

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